Pre-loaded resin for synthesis of peptide acids containing a side-chain modified C-terminal lysine amino-acid residue by Fmoc SPPS. The Mtt group can be removed selectively on the solid phase with 1% TFA in DCM, unmasking the side-chain lysine amino group for further functionalization.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Linkage
Replaces: 04-12-2067
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 – 1.00 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene – 1% DVB) 100 -200 mesh.
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